On October 14, 2025, during Oracle AI World in Las Vegas, Oracle announced a significant partnership with Children’s Hospital Los Angeles (CHLA), a top-ranked pediatric hospital and research center. The collaboration highlights CHLA’s adoption of Oracle’s Autonomous AI Database on Oracle Cloud Infrastructure (OCI) to dramatically boost the performance of its mission-critical business systems – achieving up to 98% improvement in speed and efficiency.

This is part of CHLA’s broader digital transformation strategy, which includes a long-term migration of key operations like finance, human resources (HR), supply chain, and customer experience to Oracle Fusion Cloud Applications. The initiative aims to modernize legacy systems (including PeopleSoft applications), enhance data security, and free up resources for patient care in a high-stakes pediatric environment.

Oracle’s major AI push was unveiled during the keynote at Oracle AI World in Las Vegas, featuring Chairman and CTO Larry Ellison and other executives. The event, formerly known as Oracle CloudWorld, shifted focus to AI as a core business differentiator. The announcements center on integrating AI deeply into Oracle’s cloud infrastructure, databases, and data platforms, aiming to make enterprise data “AI-ready” while emphasizing security, scalability, and agentic automation (AI agents that can act autonomously). This builds on Oracle’s prior AI efforts, like embedding AI agents in cloud apps and partnerships for large language model (LLM) training.

CHLA plans pilot programs for advanced AI features, like predictive analytics for patient resource allocation, and potential expansions into machine learning for research data. Success will be tracked via metrics like reduced processing times and staff satisfaction, with possible joint publications to guide the sector. This could accelerate Oracle’s penetration in U.S. healthcare, especially among academic medical centers, amid a market projected to exceed $50B for cloud AI in health by 2027.

Oracle Health (formerly Cerner) competes in electronic health records (EHRs), cloud infrastructure for healthcare, AI-driven analytics, revenue cycle management (RCM), and enterprise resource planning (ERP) for providers like hospitals and clinics. Its strengths lie in integrated AI agents, autonomous databases on Oracle Cloud Infrastructure (OCI), and end-to-end solutions post-2022 Cerner acquisition.

However, it faces stiff competition from EHR giants, cloud hyperscalers with healthcare-specific offerings, and specialized analytics/RCM vendors. Oracle holds about 23% market share in acute care EHRs (as of 2024 data), trailing leaders like Epic.Epic leads with customization, but Oracle’s “voice-first” AI EHR aims to differentiate via OCI’s semantic database for “army of AI agents.” KLAS reports mixed Oracle satisfaction but optimism for AI features.